Three different organizations of this protein, some parallel some perpendicular to the plane of the nuclear envelope.
Daily Archives: March 1, 2016
Nuclear envelope: nuclear membranes and related proteins: loop of DNA video
I continued to be interested in this image of a guinea pig alveolar type Ii cell nucleus, just off to the side which had a couple areas that looked for all the world as if they were part of some coiling of (coiling of the 30 nm coil) and maybe even linked together in a similar fasion as the nucleosomes themselves, but maybe packages of 3 or 4 nucleosomes with a linking region that looked to be consistent as well. Video is primitive, but it does give relevancy to the big-beads (to be distinguished from the more commonly used “beads” on a string for nucleosomally wound DNA. I really have scoured the internet and science articles to find another who has seen this kind of arrangement of chromatin at the periphery of the nucleus…. I have not found much. Nucleosomes are typically NOT as large as these one-step-further- wound DNA. Video is here:
Here is an awesome picture (diagram) which i found after making my short video…. the link to the diagram and those who made it is here. www.cell.com/molecular-cell/fulltext/S1097-2765%2810%2900172-3