This micrograph has some interesting features for an ostensibly normal mouse liver: normal in that it is part of a study on Gclc loss, which causes early death  (specifics and article here) but this liver should not have had so many vesicles within vesicles as seen in the Gclc ko mice, and typically they are vesicles within vesicles without ribosomes.  here there are vesicles within the vesicles of RER …17941_73225_liver_Albwc_Gclcii_1mo_no_NAC