Alveolar macrophage from a mouse lung, the latter having been subjected to complete submersion in E2 perfluorochemical for three hours, and allowed to recover for 48 hours.

A single macrophage has almost all the PFC inclusions with high concentrations of enzymes, making them appear to have black “caps” in some cases, and in others, mostly enzymes, showing the tiny E2 particles and larger particles (does anyone know if this is Oswald ripening…. it seems as if the particles are doing two things, getting smaller and coalescing…??). The variety of multivesicular bodies here is quite amazing, with some having other structures included, some being filamentous, mostly being very very electron dense.  Each of the MVB/LE with PFC inclusions (i did not tag them all, it was too cluttered) have a bounding box indicated on the unretouched first image,  they are all enlarged and collected in a gallery below (numbered so you can find them).  Compare the variety here with three other posts on MVB/LE/PFC.