Category Archives: Sara-Witts-end

What kind of diagram is this? mitochondrial cristae

I find that diagrams and illustrations for science are so often NOT GOOD, NOT EXPLANATORY, and are TOTALLY CONFUSING.  Here is an example. It is from a very nice article, (Biochimica et Biophysica Acta 1793 (2009) 5–19), but the diagrams of the arrangement of cristae just doesn’t make visual sense.  It is an injustice to readers to create confusing images and put them up as learning aids.  THis diagram misuses the shading when it creates a look of 3dimsnsions…. it makes no visual sense in any of the three drawings in this figure.  To create shading on one portion of a diagram (e.g. the middle figure) which in this case was the intercristae space, which is called the intermembrane space, and NOT make the shading equivalent on the mitochondrial matrix is just careless, and misleading. The lower diagram is beyond deciphering…. it looks like there are three orange fingers poking up, from a space with holes.  Nothing resembling anything that is shown with real TEM images.  So sad.  It wastes time and  sends wrong information.

Job

Job 5:7 Yet man is born to trouble as surely as sparks fly upward.

Job 7:9 My days are swifter than a weaver’s shuttle, and they come to an end without hope.

Job 9:25 My days are swifter than a runner; they fly away without a glimpse of joy.

Great prose on life’s miseries, and every bit as beautiful as Shakespeare.

If you are a —

If you’re free-thinking, they will think of you as a trouble-maker

but, if you’re a conformist, they will think of you as weak
——————————————
If you’re educated they will call you egotistical

but if you aren’t, they will call you stupid
——————————————
If you work but can’t support your family, they will call you lazy

but, if you work 2 jobs, they will call you a bad parent
——————————————
If you don’t have a car, they will think less of you

but, if you have a nice car they will think you’re pretentious
——————————————
If you stick by people that do you wrong, they will call you a fool

but if you cut people out of your life, they will call you disloyal
——————————————
If you are overweight they will call you unattractive

but if you diet and exercise, they will call you vain
——————————————
If you don’t do your makeup and your hair, they consider you ugly

but if you do, they consider you fake
——————————————
If you didn’t vote they will tell you were negligent

but, if you did, they will tell you it was for the wrong person
——————————————
If you were born with the help of affluent parents, you will be “entitled”

but, if you take help from others you will be a “freeloader”
——————————————

There are 10,000 ways to skin a cat.
In a world we have created, in which NOBODY is ever “doing it right,” wrong opinions abound, and everybody has one… but also, everybody has the right to be opinionated. WHO DOESN’T SEIZE THAT OPPORTUNITY!!

Just as long as that individual isn’t causing me personal problems, and mine isn’t doing the inverse… then let’s just ALL be the biggest that we can be!

Just do everybody a favor and CLENCH when you feel the urge to deliver MORE than JUST your opinions on people.

Febreze syndrome: fake news: fake odor removal: fake politics – ill-advised fakes for the 21st century

cyclodextrin and fake news and fake odor removalWhat about policies for government, business, and personal morality in the 21st century? An alarming trend is that we FEBREZE (everything, our homes, our clothes, our bodies, our jobs, our policies, and our morals. I am going to use febreze in a broad sense, while actually saying something about the actual product Febreze (hydroxypropyl beta-cyclodextrin) as the motif. Why do i use febreze as an example? Because what P&G claims for febreze is a lie, it is also a perfect example of our national crisis in respect to fake news. This industry giant has claimed that febreze eliminates odors, which it certainly does NOT, it masks odors, the two don’t equate. If one dissects their statement, you have to agree that their claim is entirely untrue.

Odor molecules are volatile organics for the most part, in my limited understanding of olfaction and the olfactory epithelium.  Whether we settle on the figure at the low end of the spectrum quoted in the literature for detectable odors (around 10,000) to the high end of the spectrum (1,000,000,000), olfaction is an important sense for us.  I wont quibble on either side of those numbers. The chemicals in air enter primarily through the nose, but also the mouth, and bind to those cute little knobs with wonderful looking sensory cilia on the top (lumental side) of olfactory epithelial cells.

Not all epithelial cells in the nose are olfactory epithelial cells, mostly it is respiratory epithelium.

But the processes and brain connections from olfaction is tied to many other systems in the body. The olfactory neurons are THE ONLY neurons in the body to make a straight path to the cortex (the olfactory cortex) all other neurons have intermediate connectors.  SO, for starters, neonatal bonding, absolutely necessary for survival and thriving, the infant being more apt so smell you than recognize your voice or face at birth. (THREAT: lots of febreze to make your nursery sweet smelling may not be that good for your baby, or their olfactory development (depressed senses) or bonding between you and your baby).

Memories from childhood about danger, about friends, about who your family and pets are is totally tied up in olfaction. In particular whether you grew up with no siblings, or in a family that was culturally related to neighbors, or more independent.  Research shows that early childhood olfactory events can contribute to at least three different kinds of (expressed by questionnaire) self-relatedness information: some being private, others more collective and those that feel part of the greater public at large (THREAT: Is it possible that the odor depleted environment produces less awareness of society in general, a more selfish and indulgent view of humanity).

Are you thinking independently when you go shopping? Not likely.  Volatile organics are pumped into many stores to increase the release of neurotransmitters, for alertness, for feeling peace and comfort which retailers deliberately want to control (the so called ambient scent and manicured right down to gender preferences. (THREAT: you many not even be aware that you are being manipulated by the marketing team of the retail store where you are…just a thought Joann fabrics always smells terrible to me… ha ha like formaldehyde, paint, plastic and preservatives offgassing, i wonder how the staff takes it and on the other extreme, the office worker down the hall sends out odors like Pier 1 imports… ha ha… totally out of context and really quite annoying.

Some odors stimulate neurotransmitter release – like that good smelling sweaty man or woman, in days gone by to ensure mating and the survival of the species (true in many species) and also to make some slippery-style guidance to have us choose “genetically similar/diverse” mates.  As a young woman i can clearly remember the “differences” in odors of those men that I dated, and it made impact on my behavior.  (THREAT: if you cant smell the mate that 100 million years of evolution has suggested for you, you may in fact make a mistake in your choice.  The remedy.. well thats for you do choose)

The smell of rotten foods, dirty surroundings, foul water, smelly sofas, garbage putting obnoxious volatile organic chemicals in the air are detected for a reason — guess what.  If it is rotten, bury it, throw it out, clean it up, don’t febreze it.  (THREAT: febreze does not eliminate odors as P&G suggests, ha ha, i puts it instead in a small basket of dextrin to trick your olfactory knobs on your olfactory epithelium into thinking that there is NO odor.  How is that eliminating odors to coat it with cyclodextrin to trick the nose…  you are breathing not only the volatile chemical but the basket used to cover it up.  Who has researched the long lasting effects of using febreze… ha ha…. go for it. NOT ME.

So the real issue here is that febreze does NOT do what it is claimed to do, it does not REMOVE odors, it masks odors, tricking the olfactory epithelium. GIVING THE OLFACTORY epithelium FAKE NEWS. Do you see where I am going with this.
Fake olfactory sensation is ok? no it isnt. Fake visual information (boob jobs, nose jobs, stomach bands, liposuction,etc etc etc) is ok? no it isn’t, one is fooling self, both psyche and morality. Fake news: well this is an entirely different blog, but the same principle. where is our morality.

Bottom line, we are all still idiots — so to speak, messing with natural functions (personal, family, child rearing, societal, dietary, pharmacologically induced)…the list is too long to waste time elaborating on…. it is everywhere and about all of it we are still clueless, and much of it is driven by profit and greed and power – what a sad commentary on humanity.

Science bashers, science deniers

Know what would be cool?? A self-correcting mechanism in which you no longer get to participate in whichever scientific or Newtonian law that you deny.

So, like, all the people that don’t believe in gravity, just fall off of the face off the earth and the vaccinations their parents were smart enough to get them just suddenly stop working.

(sara-witts-end.com)

I could add to this list, many times over, those who deny historical events with so much evidence that one would have to reject all of our previous history to deny; those who deny climate change (that is just so laughable…. of course the climate changes, and will change, and it has nothing to do with whether we caused it or not, it is going to change (not to excuse any wasteful non-environmental-hedonist behavior)…just to name 2.

So the next level of investigations take us to NASA’s description of gravity and microgravity. HERE. Awesome. And here are some definitions from their site.

Words to Know:
Free fall: the condition of moving freely in an environment in which gravity, and nothing else, is causing acceleration
Vacuum: the absence of all matter, including air
Mass: the measurement for the amount of matter in an object

 

Sara-Witts-end: awesome thoughts

Yeah, so maybe I’m a little salty this morning because I got woken-up by Bizzy shanking my right nostril with her toenail, but……
Sometimes I look around, and I’m astounded at how good and accepting people can be. Other times I wake up and I am BAFFLED at where we still are as a species.
Look at us. Look around. If it isn’t sprouting from the ground, visible on a clear night, warming your back and lighting the sky, or falling from it, then we as humans, likely made it.
Our brains are astonishing. We can solve numerical equations and riddles of physics, cure disease, we can build beautiful homes, luxurious cars, and things that catapult us miles and miles across the sky just for shits and giggles.
We have figured out how to communicate with thousands of people at once, using little palm-sized, picture taking, artificially intelligent entertainment boxes.

But you know what we can’t seem to do with our brains, complete with the most complex frontal lobes of any being???
We can’t seem to figure out how to be nice to one another. Seems like a huge waste to me.

If we were less sentient beings that couldn’t crawl out from under our animalistic instincts, it would be excusable.
But, it’s sad to think we are so superbly equipped to do good things by one another, and not just MAKE good things for OURSELVES, while we dismantle the people around us…. and we can’t seem to get it.

If there IS some cosmic “thing” observing our behavior, then I bet you he/she/it is highly disappointed.

REPOSTED from Sara Witts facebook page (without her permission i might add, but i am her mom>>>>!!!!