Tangential cuts through alveolar type II cell granules show dense layer substructure

Tangential cuts through alveolar type II cell granules show dense outer layers of this regularly arranged molecular substructure, has a periodicity to it, albeit densities of a different size than at other sites in the , just like the less dense middle band of these granules.  Images below also show a slight tendency for vertical banding, within the horizontal layers of the surfactant protein (A ? ) granule. The hierarchy for all the level of substructural organization are here:

  1. 100 nm period (height) (no restriction on length of granule seen) which has 1,3,5 or 7 layers between the outer dense bands
  2. Outer dense layers on perpendicular cut look continuous, on tangential cut however, they show a periodicity with large round densities about 2.5 per 100 nm length.
  3.  Moderately dense central band shows a periodicity of 5-7 densities per 100 nm
  4. vertical stripes, a kind of banding, perpendicular to the long orientation of mos that coinciding with the periodicity of the central dense  band.

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