Variety: the whole spectrum of lysosomes/inclusions of E2 in an alveolar macrophage

Variety: the whole spectrum of lysosomes/inclusions of E2 in this micrograph of an alveolar macrophage (at least the whole variety I have seen so far). It includes lysosomes (LE/LY/PFC) which probably could be classified all the way from golgi vesicles to late endosomes since it seems that PFCs in general are able to work their way into the whole ER system (though to date I have not seen anything that looks like a PFC droplet in any ER which has ribosomes….  still looking). There are droplets in a “hollow” meaning no lysosomal enzymes yet, on the right but still having E2 droplets with the coating they must pick up from somewhere (maybe alveolar surfactant in the alveolar space?, being lipid and E2 being slightly lipophilic), to the dense small lysosomes with many E2 droplets on the left, to a single E2 droplet on the lower left, and a dozen droplets which look like they are hanging out in the cytosol with no membrane boundaries, to bottom center structure which looks like two E2 droplets in a lysosome with a lamellar type surfactant inclusion.

There is no paucity of free ribosomes in this cropped image, and size can be inferred from the approximate 27nm diameter of a ribosome (red dot), to the larger droplet size (bar=270nm).