Intracisternal granule from alveolar type II cell of the guinea pig

Nucleus, other organelles, nuclear pore, intracisternal protein accumulation, perichromatin granules, and part of the basement membrane are labeled in this electron micrograph of a type II cell from the lung of a guinea pig. Nucleus is on the right and a very thin band of cytoplasm is present, then there is the extracellular space (with basement membranes and parts of other cell processes).  Basement membrane – purple arrow and label; red arrow and label – nuclear pore; black arrow and label – intracisternal protein which might be surfactant protein A (overproduced). Perichromatin granules (adjacent to heterochromatin) are shown by blue arrows and label.

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