Monthly Archives: September 2016

Cover submission to JBC which was a finalist but didn’t make the cut

How awesome is this composite of gastric epithelium (light micrographs) put together in a collage of images with the forestomach images in the upper right outside, and the glandular stomach on the outside lower left and bottom and all the glandular stomach epithelium at lower magnification with light microscopy surrounding two higher magnification (100x at least) images within the center.  Too bad this didn’t make it on the cover of JBC.  Here is a mockup of what could have been.  LOL.   Still a great image.  I have to consider these cover rejections as just part of the competition in scientific illustration.

A7_A9_cover_draft_for_JBC_3

Parietal cell (stomach, mouse) with some organelles diagrammed

More images of gastric epithelium in the mouse, onto which is layered some vector graphics of mitochondria, vesicles, nucleus (pale condensed chromatin areas within, nuclear membrane (inner and outer membrane and perinuclear space — but no nuclear pores are identified here specifically but the places where outer and inner nuclear membrane come together nuclear pores would be found.  This is color and information together, for the 21 century and the digital age.

The microvillar (highly microvillar) apical membrane is shown, the lateral membrane and basal membrane are not distinguished from each other except as the bottom of the diagram is basal.

parietal_cell_pseudo-colored_with_diagram

Cardiac muscle cell and ion pumps diagram

This illustration, a background of cardiac muscle cell (mitochondria blue; myofilaments, myofibrils, purple) with an overlay of a rectangle representing a cell (no plasmalemma distinctions on this box) showing some of the ion pumps that are responsible for homeostasis and function in cardiac muscle.  This was a cover submission to Journal of Biological Chemistry, years ago, and unfortunately I had two cover submissions for the same month…. this one lost to my other one (ha ha). That was a banner month for me. Two submissions to the same journal but I just wish that either one or the other of the first authors on those manuscripts would have opted to delay publication one month, as I thought this was a pretty good graphic.

cardiac_muscle_ion_pump_cover_submission

Too crazy to submit as a cover illustration of an alveolar type II cell diagram

Ha ha…. There are few things in life that I love more than illustrating science.  I don’t belong to any group of medical illustrators though this was the dream that began my career in science.  I do wish I could send well wishes to long-ago-deceased Lucille Castle Innes who lived next door to me (and the family) at 5252 Windermere in Los Angeles California.  It is to her that I give credit for introducing me to scientific illustration.

I remember showing her a diagram of a muscle cell, which apparently I was proud of, and that was likely a school assignment (Eagle Rock High School in the class of a woman whose name I have forgotten (I do, ha ha, think she was the archetypal spinster scientist lady-high school teacher)), but Mrs. Innes mentioned to me that I has not spelled “striated” muscle correctly.  Never since have I missed that word.  Ha Ha.  Mrs Innes not only gave me instructions, inspiration, but also landed me my first job at White Memorial Hospital in LA where I helped sort 2×2 slides of diseases and stuff, watched my first autopsy (lordy, I remember nearly passing out) and watching her work, and receiving guidance when wanting to enroll in a medical illustration degree course (which I did, at the University of Toronto, under the directorship of Nancy Joy).

As life would have it, those aspirations of being a medical illustrator were derailed and I ended up at the University of Cincinnati, in Anatomy, but always illustrated and worked up my own graphics, earning the not so wonderful title from a less than supportive Director of Toxicology during my time in the Department of Environmental Health where I did electron microscopy aka, comparative anatomy and pathology  — the Queen of Corel.  By way of admission to absolutely loving a program, I have to say CorelDRAW just works for me….  ever since the very first version on 11 little pink floopies, downloaded (probably not legally) from a local print store.  Since then, CorelDRAW (versions 4, 6, 10, X3 and 15 have been a life-mainstay).  So very different from the hand made stippling and little circles in the first scientific illustrations I did decades ago, now it is diagrams like this one below, of an alveolar type II cell. Just loads of fun, and color appeal but still full of good scientific information.

This particular andy-warhol-style-diagram of a parenchymal cell in the lung was just a little too wild as a cover submission to submit along with my editorial on the  ANATOMY OF AN ALVEOLAR TYPE II CELL DIAGRAM .

alveolar_type_II_cell_diag_cov_sub_5

alveolar_type_II_cell_diag_cov_sub_5a