Guinea pig (now the most posted alveolar cell-RER granules (intracisternal bodies) in history (LOL) guinea pig # 301.  This is a very very large protein accumulation, and somewhat different in morphology than the typical intracisternal body (seen adjacent, below) and I don’t know yet why the difference in structure.  This guinea pig, that is, the guinea pig 301 which continually showed the greatest number of RER granules of any other animal in this archival set of micrographs, and interestingly it possesses some distinct prismatic (rhomboidal) regular bodies that resemble virus particles (more data needed).  It would be awesomely consistent with what is known about surfactant protein A and innate immunity to have this guinea pig demonstrate first hand what kind of an increase in surfactant proteins (either A or D) to respond to a viral infection.  We will see.

This granule rivals in size the nucleus in the adjacent alveolar type II cell.