Estimates of the size of some nucleolar components

This micrograph, parts of which have been seen before, is an hepatocyte nucleus which is in the early stages of demise (untreated CoS14 ko without rescue). The nucleolus is large, and has two cajal type bodies (one seen here) and fibrillar centers with fairly large densities within (of approximately 90 nm diameter). I have given these sizes (relative to a ribosome size red dot approximately 27 nm (lower right hand side of micrograph labeled as such). The granules within the granular portion of the nucleolus (as well as the banding patterns found on cajal bodies) is something around 23 nm.  What I presume to be perichromatin granules look to be about 50 nm. The large dense bodies within the fibrilar centers are a little unusual.