LSm protein Hfq hexamer torus (search wikipedia for their image below ). This is going to be an awesome hunt, especially in the hepatocyte nuclei in the 14CoS ko mice where the hepatocytes undergo a pan-apoptosis, synchronized across the entire liver. There will be (I predict) many cases where this group of proteins will cause clearly visible electron microscopic ultrastructure in that process. The ultrastructure of the nucleus is determined by the status of ribosomes production.
Life is such a mix of mundane and completely outrageous… ha ha….. felt compelled to clean a few gutters of oak catkins before predicted-storm for this afternoon…an important but “nothing” task, then treked into work, and happened to look at a structure in an old electron micrograph of CoS 14 mouse hepatocyte, micrograph looking like something between a coiled strand of DNA and a Cajal body adjacent to a nucleolus, and find of course this enormous field of protein research on small nuclear RNAs, which I had only hear of briefly and know nothing about…. Oh my god…. How big and unknowable is the known (pun intended) universe… and what unfathomable event-entity could have brought it all into being…. Makes me “fearful” ha ha ha… just like those old Hebrews — they knew of and felt an awesomeness of nature/biology/cosmos that we don’t think of today since we are insulated by tech and devices.