Daily Archives: August 11, 2017

MVB/LE/PFC: multivesicular bodies, late endosomes, perfluorochemical inclusions

Alveolar macrophage from a mouse lung, the latter having been subjected to complete submersion in E2 perfluorochemical for three hours, and allowed to recover for 48 hours.

A single macrophage has almost all the PFC inclusions with high concentrations of enzymes, making them appear to have black “caps” in some cases, and in others, mostly enzymes, showing the tiny E2 particles and larger particles (does anyone know if this is Oswald ripening…. it seems as if the particles are doing two things, getting smaller and coalescing…??). The variety of multivesicular bodies here is quite amazing, with some having other structures included, some being filamentous, mostly being very very electron dense.  Each of the MVB/LE with PFC inclusions (i did not tag them all, it was too cluttered) have a bounding box indicated on the unretouched first image,  they are all enlarged and collected in a gallery below (numbered so you can find them).  Compare the variety here with three other posts on MVB/LE/PFC.

BOOM

Thus TWEETS the president: “Military solutions are now fully in place, locked and loaded, should North Korea act unwisely. Hopefully Kim Jong Un will find another path! ”   so sad to say but THESE ARE BOTH DUCKS OF THE SAME FEATHER.  Who says stuff like this except individuals who are just not in touch with reality, nor do they care about anything except their self esteem (which in both cases is below my shoe sole).  This is Lose-Lose…since we already know Kim Jong Un will be unwise, as will be Trump.

and did trump really tweet this in january… apparently so.

“North Korean Leader Kim Jong Un just stated that the “Nuclear Button is on his desk at all times.” Will someone from his depleted and food starved regime please inform him that I too have a Nuclear Button, but it is a much bigger & more powerful one than his, and my Button works!”   what a dumbnut.